Age-standardized functions out of 86,149 women in the newest NHS We from inside the 1994 and 94,715 ladies in brand new NHS II from inside the 1995 because of the quintiles regarding magnesium, potassium, and you may calcium intakes step one
Design 2 is actually adjusted in terms of design step one and intakes from potassium and you may calcium supplements (quintiles of grams/d)
On the multivariate analyses, full and dieting magnesium intakes was indeed inversely for the risk of overall but ischemic otherwise hemorrhagic heart attack ( Table 2). The fresh new pooled multivariate RR to own complete stroke are 0.87 (95% CI: 0.78, 0.97; P-trend = 0.07) towards review of females regarding the high which have reduced quintiles off total magnesium consumption; whereas brand new pooled multivariate RR to the assessment regarding large that have lower quintiles out-of weight-loss magnesium intake try 0.81 (95% CI: 0.69, 0.94; P-pattern = 0.001) to own overall coronary arrest. Full potassium consumption is inversely associated with threat of total however, not ischemic or hemorrhagic heart attack ( Table step three). To have comparison of women regarding high having lower quintiles out-of complete potassium consumption, new pooled multivariate RR getting full coronary attack try 0.89 (95% CI: 0.80, 0.99; P-trend = 0 LDS single dating site.01). Multivariate RRs both for magnesium and potassium was attenuated whenever all the step 3 nutritional elements was in fact included in the models at the same time (multivariate model 2). There can be no tall organization ranging from total or weight reduction calcium supplements intake and you may overall, ischemic, otherwise hemorrhagic coronary arrest ( Dining table cuatro). Multivariate RRs for complete magnesium (Extra Dining table 1), overall potassium (Supplemental Dining table dos), overall calcium supplements (Supplemental Desk 3), weight-loss magnesium (Extra Table cuatro), fat loss potassium (Supplemental Table 5), and you will dietary calcium (Supplemental Table 6) and you will chance of full, ischemic, and you will hemorrhagic strokes each cohort separately receive on supplemental question.
Pooled RRs (95% CIs) out of overall, ischemic, and you will hemorrhagic shots because of the quintiles away from overall and you can weight-loss magnesium consumption when you look at the 86,149 feamales in the newest NHS We and you may 94,715 feamales in brand new NHS II 1
Values are the n of cases. Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.
Pooled RRs (95% CIs) out-of overall, ischemic, and you will hemorrhagic shots because of the quintiles off total and you may dietary magnesium intake within the 86,149 women in new NHS We and you may 94,715 ladies in the new NHS II 1
Values are the n of cases. Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.